THC Science

CALN1
Identifiers
Aliases	CALN1, CABP8, calneuron 1
External IDs	OMIM: 607176 MGI: 2155987 HomoloGene: 10966 GeneCards: CALN1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	72,447,151 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	130,876,253 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Orthologs
	83698
	140904
	ENSG00000183166
	ENSMUSG00000060371
	Q9BXU9
	Q9JJG7
	NM_001017440; NM_031468; NM_001363460
	NM_021371; NM_181045
	NP_001017440; NP_113656; NP_001350389
	NP_067346; NP_851388
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.^[5]^[6] Alternative splicing results in multiple transcript variants.^[6]

Function[edit]

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183166 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060371 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.
^ ^a ^b "Entrez Gene: CALN1 calneuron 1".
^ McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.

External links[edit]

Human CALN1 genome location and CALN1 gene details page in the UCSC Genome Browser.

Further reading[edit]

Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Sanger Centre, The; Washington University Genome Sequencing Cente, The (Nov 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183166 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060371 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11286509-5] Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.

[entrez-6] "Entrez Gene: CALN1 calneuron 1".

[pmid_20668007-7] McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.

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Function[edit]

References[edit]

External links[edit]

Further reading[edit]

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