Cannabidiol: State of the art and new challenges for therapeutic applications.

Pisanti S1, Malfitano AM2, Ciaglia E2, Lamberti A2, Ranieri R2, Cuomo G2, Abate M2, Faggiana G2, Proto MC3, Fiore D3, Laezza C4, Bifulco M5. Author information 1Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Italy. Electronic address: spisanti@unisa.it. 2Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Italy.… Continue reading Cannabidiol: State of the art and new challenges for therapeutic applications.

Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression

Robert J. McKallip, Wentao Jia, Jerome Schlomer, James W. Warren, Prakash S. Nagarkatti and Mitzi Nagarkatti Molecular Pharmacology September 2006, 70 (3) 897-908; DOI: https://doi.org/10.1124/mol.106.023937 Abstract In the current study, we examined the effects of the nonpsychoactive cannabinoid, cannabidiol, on the induction of apoptosis in leukemia cells. Exposure of leukemia cells to cannabidiol led to… Continue reading Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression