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Names | |
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IUPAC names
[(2R,3R,4S)-3,4,5-trihydroxy-5-
(hydroxymethyl)oxolan-2-yl] methoxyphosphonic acid |
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Other names
β-D-fructose 6-phosphate,
fructose 6-phosphate |
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Identifiers | |
643-13-0 ![]() |
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Abbreviations | F6P |
ChEBI | CHEBI:16084 ![]() |
ChemSpider | 392657 ![]() |
Jmol interactive 3D | Image |
PubChem | 444848 |
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Properties | |
C6H13O9P | |
Molar mass | 260.14 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Fructose 6-phosphate (also known as the Neuberg ester) is fructose sugar phosphorylated on carbon 6 (i.e., is a fructosephosphate). The β-D-form of this compound is very common in cells. The vast majority of glucose and fructose entering a cell will become converted to this at some point. The name Neuberg ester comes from the German biochemist Carl Neuberg.
History[edit]
In 1918, Carl Neuberg found that the compound (only later identified as fructose 6-phosphate) could be produced by mild acid hydrolysis of "Harden-Young ester" (fructose 2,6-bisphosphate).[1]
Fructose 6-phosphate in glycolysis[edit]
Fructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate. It is in turn further phosphorylated to fructose-1,6-bisphosphate.
α-D-glucose 6-phosphate | Phosphoglucose isomerase | β-D-fructose 6-phosphate | Phosphofructokinase-1 | β-D-fructose 1,6-bisphosphate | ||
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ATP | ADP | |||||
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Pi | H2O | |||||
Phosphoglucose isomerase | Fructose bisphosphatase |
Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Enzyme 2.7.1.11 at KEGG Pathway Database. Enzyme 3.1.3.11 at KEGG Pathway Database. Reaction [1] at KEGG Pathway Database. Compound C05378 at KEGG Pathway Database.
Click on genes, proteins and metabolites below to link to respective articles. [§ 1]
- ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".
See also[edit]
Glycolysis Metabolic Pathway | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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References[edit]
- ^ Fruton, Joseph S. Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology. Yale University Press: New Haven, 1999. p 292