Cannabis Ruderalis

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Clinical data
Other names5-Fluoro EDMB-PINACA
Legal status
Legal status
  • Ethyl (S)-2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate
CAS Number
PubChem CID
Chemical and physical data
Molar mass391.487 g·mol−1
3D model (JSmol)
  • O=C(N[C@H](C(OCC)=O)C(C)(C)C)C1=NN(CCCCCF)C2=C1C=CC=C2
  • InChI=1S/C21H30FN3O3/c1-5-28-20(27)18(21(2,3)4)23-19(26)17-15-11-7-8-12-16(15)25(24-17)14-10-6-9-13-22/h7-8,11-12,18H,5-6,9-10,13-14H2,1-4H3,(H,23,26)/t18-/m1/s1

5F-EDMB-PINACA is a designer drug and synthetic cannabinoid.[1][2] In 2018, it was the fourth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.[3]

In the United States, 5F-EDMB-PINACA was temporarily emergency scheduled by the DEA in 2019.[4] and made a permanent Schedule I Controlled Substance on April 7, 2022.[5]


  1. ^ Liu C, Jia W, Hua Z, Qian Z (2017). "Identification and analytical characterization of six synthetic cannabinoids NNL-3, 5F-NPB-22-7N , 5F-AKB-48-7N , 5F-EDMB-PINACA, EMB-FUBINACA, and EG-018". Drug Testing and Analysis. 9 (8): 1251–1261. doi:10.1002/dta.2160. PMID 28063270.
  2. ^ "5F-EDMB-PINACA" (PDF). NMS Labs.
  3. ^ "Emerging Threat Report: Annual 2018" (PDF). Special Testing and Research Laboratory, Drug Enforcement Administration. Archived from the original (PDF) on 2019-08-01. Retrieved 2019-08-03.
  4. ^ "Schedules of Controlled Substances: Temporary Placement of 5F-EDMB-PINACA, 5F-MDMB-PICA, FUB-AKB48, 5F-CUMYL-PINACA, and FUB-144 into Schedule I". Federal Register. 2019-04-16.
  5. ^ "Schedules of Controlled Substances: Placement of 5F-EDMB-PINACA, 5FMDMB-PICA, FUB-AKB48, 5F-CUMYLPINACA, and FUB-144 in Schedule I" (PDF). Federal Register. 87 (67). 2022-04-07.

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