Prolactin-releasing peptide receptor

Aliases PRLHR, GPR10, GR3, PrRPR, prolactin releasing hormone receptor
External IDs MGI: 2135956 HomoloGene: 3134 GeneCards: PRLHR
Gene location (Human)
Chromosome 10 (human)
Chr. Chromosome 10 (human)[1]
Chromosome 10 (human)

Genomic location for PRLHR
Genomic location for PRLHR
Band 10q26.11 Start 118,589,997 bp[1]
End 118,595,648 bp[1]
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 10: 118.59 – 118.6 Mb Chr 19: 60.47 – 60.47 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

The prolactin-releasing peptide receptor (PrRPR) also known as G-protein coupled receptor 10 (GPR10) is a protein that in humans is encoded by the PRLHR gene.

PrRPR is a G-protein coupled receptor[5] that binds the prolactin-releasing peptide (PRLH).[6]


PrRPR is a 7-transmembrane domain receptor for prolactin-releasing peptide that is highly expressed in the anterior pituitary.[7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119973Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045052Ensembl, May 2017
  3. ^ “Human PubMed Reference:”.
  4. ^ “Mouse PubMed Reference:”.
  5. ^ Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P (1995). “Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors”. Genomics. 29 (2): 335–44. doi:10.1006/geno.1995.9996. PMID 8666380.
  6. ^ Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M (1998). “A prolactin-releasing peptide in the brain”. Nature. 393 (6682): 272–6. doi:10.1038/30515. PMID 9607765.
  7. ^ “Entrez Gene: PRLHR prolactin releasing hormone receptor”.

Further reading[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.