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AM-6545 AM-6545Identifiers IUPAC name 5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide CAS Number1245626-05-4 NPubChem CID46912919ChemSpider26333263 YCompTox Dashboard (EPA)DTXSID70677329 ECHA InfoCard100.216.518 Chemical and physical dataFormulaC26H23Cl2N5O3SMolar mass556.463 g/mol g·mol−13D model (JSmol)Interactive image SMILES O=S4(=O)CCN(CC4)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(c1C)-c3ccc(C#CCCC#N)cc3 InChI InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) YKey:XBHQLFVDGLPBCK-UHFFFAOYSA-N Y  NY (what is this?) AM-6545 is a drug which acts as a peripherally selective silent antagonist for the CB1 receptor, and was developed for the treatment of obesity. Other cannabinoid antagonists… read more »

Research

AM-6545 AM-6545Identifiers IUPAC name 5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide CAS Number1245626-05-4 NPubChem CID46912919ChemSpider26333263 YCompTox Dashboard (EPA)DTXSID70677329 ECHA InfoCard100.216.518 Chemical and physical dataFormulaC26H23Cl2N5O3SMolar mass556.463 g/mol g·mol−13D model (JSmol)Interactive image SMILES O=S4(=O)CCN(CC4)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(c1C)-c3ccc(C#CCCC#N)cc3 InChI InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) YKey:XBHQLFVDGLPBCK-UHFFFAOYSA-N Y  NY (what is this?) AM-6545 is a drug which acts as a peripherally selective silent antagonist for the CB1 receptor, and was developed for the treatment of obesity. Other cannabinoid antagonists… read more »

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AM-6545 AM-6545Identifiers IUPAC name 5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide CAS Number1245626-05-4 NPubChem CID46912919ChemSpider26333263 YCompTox Dashboard (EPA)DTXSID70677329 ECHA InfoCard100.216.518 Chemical and physical dataFormulaC26H23Cl2N5O3SMolar mass556.463 g/mol g·mol−13D model (JSmol)Interactive image SMILES O=S4(=O)CCN(CC4)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(c1C)-c3ccc(C#CCCC#N)cc3 InChI InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) YKey:XBHQLFVDGLPBCK-UHFFFAOYSA-N Y  NY (what is this?) AM-6545 is a drug which acts as a peripherally selective silent antagonist for the CB1 receptor, and was developed for the treatment of obesity. Other cannabinoid antagonists… read more »

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