FUB-APINACA

FUB-APINACA
FUB-APINACA.png
Legal status
Legal status
Identifiers
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C25H26FN3O
Molar mass 403.5 g/mol g·mol−1
3D model (JSmol)

FUB-APINACA or AFUBINACA (also known as FUB-AKB48) is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1] It is an analogue of APINACA and 5F-APINACA where the pentyl chain has been replaced with fluorobenzyl.

Pharmacology[edit]

FUB-AKB-48 acts as a full agonist with a binding affinity of 1.06nM at CB1 and 0.174nM at CB2 cannabinoid receptors.[2]

Legal status[edit]

Sweden’s public health agency suggested classifying FUB-APINACA as a hazardous substance on November 10, 2014.[3]

It is also illegal in Alabama (listed as FUB-AKB48).[4]

See also[edit]

References[edit]

  1. ^ “FUB-AKB48”. Cayman Chemical. Retrieved 23 July 2015.
  2. ^ Hess, Cornelius; Schoeder, ClaraT.; Pillaiyar, Thanigaimalai; Madea, Burkhard; Müller, ChristaE. (1 July 2016). “Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice”. Forensic Toxicology. 34 (2): 329–343. doi:10.1007/s11419-016-0320-2. ISSN 1860-8965. PMC 4929166. PMID 27429655.
  3. ^ “Cannabinoider föreslås bli klassade som hälsofarlig vara”. Folkhälsomyndigheten. Retrieved 23 July 2015.
  4. ^ Alabama Senate Bill SB 333: Controlled Substances