X41 may refer to:
- Ear Force X41, headset designed by Turtle Beach Systems for use with the Xbox 360 video games console
- IBM Thinkpad X41 laptop computer by Lenovo
- Mission X-41, episode 27 of the Gerry Anderson television series Joe 90
- X-41 (yacht), designed by X-Yachts Design Team led by Niels Jeppesen and first launched in 2007 to follow on from the X-35
- X-41 Common Aero Vehicle, the designation for a still-classified U.S. military spaceplane
- Red Express X41 line, a bus route in the United