Van Wie or Vanwie or variation, may refer to:

• Van Wie Creek, a tributary of the Mohawk River in New York State, US

• David Van Wie (born 1964) U.S. inventor
• Derrick Vanwie, a member of the hardcore band One King Down
• Joel VanWie, a member of the pop-punk band The Last Sleepless City
• Virginia Van Wie (1909-1997) U.S. golfer

• Wie (disambiguation)
• Van (disambiguation)
• Van Wieren, a surname