Rhodope may refer to:

• Rhodope (mythology), a figure of Greek mythology
• Rhodope Mountains, in Bulgaria and Greece
• Rhodope (regional unit), of Greece
• Rhodope (province), a Roman and Byzantine province
• 166 Rhodope, an asteroid
• Rhodope (genus), a genus of the family Rhodopidae, order Rhodopemorpha, class Gastropoda
• Mylothris rhodope, a dotted border butterfly of tropical Africa commonly known as the Rhodope