Interstate 80 Business (BL-80) is a business loop of Interstate 80 (I-80) that is 2.26 miles (3.64 km) long and serves as the main street for the towns of West Wendover, Nevada and Wendover, Utah along a roadway named Wendover Boulevard. Wendover Boulevard was originally part of U.S. Route 40 (US 40), which connected California to New Jersey via Nevada and Utah. A portion of the Nevada segment is concurrent with U.S. Route 93 Alternate (US 93 Alt.), and the entire portion in Utah is coterminous with Utah State Route 58 (SR-58). The Nevada Department of Transportation (Nevada DOT) applied for the business loop designation in the early 1980s but the designation has never been approved, despite signs being posted in both states. Between July 1976 and 1993, BL-80 was concurrent with State Route 224 (SR 224) in Nevada.

Recently selected: Capitol Loop • Interstate 40 in Arizona • Minnesota State Highway 610