Oke or OKE may refer to:

• Omicron Kappa Epsilon Fraternity
• Ōke, branches of the Japanese Imperial Family
• Oka (mass), an Ottoman measure of mass
• Oke (name)
• Oke, Alberta, a locality in Yellowhead County, Alberta, Canada
• Okinoerabu Airport, Kagoshima Prefecture, Japan (IATA airport code: OKE)
• Okehampton railway station, England (station code OKE)
• Okpe language (Southwestern Edo), an Edoid language of Nigeria (ISO 639-3 code: oke)
• Oke or oké, variations of okay
• OKE: Operation Kill Everything, 2013 mixtape by The Game