MSB may refer to:
- Main Support Battalion, part of the U.S. Army logistics
- Maritime Services Board, former government agency in New South Wales, Australia
- Marshall Swift-Boeckh, a cost estimation services provider and subsidiary of CoreLogic
- Le Mans Sarthe Basket a French basketball team
- The Magic School Bus, series of children's books about science
- Media Stream Broadcast, a proprietary, multicast communications protocol owned by Microsoft
- 1,4-Bis(2-methylstyryl) benzene, also known as p-Bis(o-methylstyryl) benzene and abbreviated Bis-MSB, a wavelength shifting compound used in liquid scintillators
- Microsoft Surface Book
- Bureau of Investigation and Statistics (Military Investigation and Statistics Bureau), the military intelligence agency of the Republic of China before 1946.
- Millennium Seed Bank, an international conservation project for storing plant seeds
- Molecular Systems Biology, an open-access, peer-reviewed scientific journal
- Money services business, a legal term used by financial regulators to describe businesses that transmit or convert money
- Most significant bit, the bit with the highest significance in a word
- Most significant byte, the highest byte in a multi-byte number
- Mrs. Stewart's Bluing, a brand of fabric bluing agent that whitens fabrics with a dye called Prussian blue (ferric hexacyanoferrate)
- Myanmar Standard Bible, a translation of the Bible into the Burmese language
- Myndigheten för samhällsskydd och beredskap, the Swedish Civil Contingencies Agency
- MSB, the Southern Railway station code for Chennai Beach railway station, Chennai, Tamil Nadu, India
Educational institutions[edit]
- Marriott School of Business at Brigham Young University
- Mason School of Business at the College of William & Mary
- McDonough School of Business at Georgetown University
- Mediterranean School of Business, is the first Business School of South Mediterranean University (SMU) in Tunisia
- Michigan School for the Blind
- Minnesota School of Business & Globe University
- Mississippi School for the Blind
- Missouri School for the Blind, Saint Louis (established 1851)
- MSB Educational Institute, a world-wide network of Islamic schools.
- Mount St Benedict College
Music[edit]
- "Megalo Strike Back", a song by Toby Fox on the album "EarthBound: I Miss You (2012)"
- Melbourne Staff Band, the premier brass band of the Salvation Army in Australia
- Michael Stanley Band, a heartland rock band from Cleveland, Ohio, USA
- MSB (album), a 1982 studio album by Michael Stanley de Devendra rajput
Video games[edit]
- Mario Slam Basketball, a 2006 video game for the Nintendo DS; aka Mario Hoops 3-on-3
- Mario Superstar Baseball, a 2005 video game for the Nintendo GameCube