The following highways are numbered 445:

• Manitoba Provincial Road 445
• New Brunswick Route 445

• Nuevitas–Camagüey Road (5–445)

• Japan National Route 445

• Florida State Road 445
• County Road 445 (Hernando County, Florida)
• Indiana State Road 445
• Louisiana Highway 445
• Maryland Route 445
• Nevada State Route 445
• New Jersey Route 445 (unsigned designation for the Palisades Interstate Parkway)
  • New Jersey Route 445S
• New Mexico State Road 445
• North Carolina Highway 445
• Pennsylvania Route 445
• Puerto Rico Highway 445
• South Carolina Highway 445 (former)
• Tennessee State Route 445
• Texas
  • Texas State Highway Loop 445
  • Farm to Market Road 445