Grossman (variants include Grosmann, Grossmann, Großmann, etc.) is a family name of Germanic origin, meaning large man.

• Achim Großmann (1947–2023), German politician
• Adam Grossman, guitarist and singer for the band Skrew
• Albert Bernard Grossman (1926 – 1986), entrepreneur and manager in the American folk music scene
• Alex Grossmann (1930–2019), Croatian-French physicist
• Allan Grossman (1910–1991), member of the Legislative Assembly of Ontario
• Allen Grossman (1932–2014), American poet; father of Bathsheba Grossman, Austin Grossman, and Lev Grossman
• Alan D. Grossman (fl. 2014?), American microbiologist
• Angela Grossmann (born 1955), Canadian artist
• Ashley Grossman (born 1993), American water polo player
• Aubrey Grossman, (1911–1999), American attorney and Communist leader
• Austin Seth Grossman (born 1969), American writer and game designer
• Avraham Grossman (born 1936), professor emeritus for Jewish history
• Bathsheba Grossman (born 1966), Santa Cruz, California artist
• Blake Grossman, chief executive officer of Barclays Global Investors
• Budd Grossman, American producer and screenwriter
• Burt Grossman, former American football defensive end
• Carl Großmann (1863–1922), German serial killer
• Christian Gottlob Leberecht Großmann (1783 –1857), German theologian
• Dave Grossman (author), American author and ex-member of the United States Army
• Dave Grossman (game developer), American game programmer and game designer
• David Grossman (born 1954), Israeli author
• Dieter Grossmann (born 1926), German painter and digital artist
• Edith Grossman (1936 – 2023), American translator from Spanish
• Emily Grossman, geneticist and science communicator
• Eric Grossman (b.1964), American bass guitarist
• Ernst August Friedrich Wilhelm Grossmann (1863–1933), German astronomer
• Gene Grossman, the Jacob Viner professor of International Economics at Princeton University
• Gheorghe Grossman, aka Gheorghe Gaston Marin (1918 – 2010), Romanian politician
• Gregory Grossman, American economist
• Gustav Friedrich Wilhelm Großmann (1746 – 1796), German actor, librettist and stage director
• Haika Grossman, Israeli politician
• Hannes Grossmann, German death metal band member
• Heinrich Ernst Grosmann (1732–1811), Danish composer
• Henryk Grossman, Polish-German economist and historian
• Ignaz Grossmann (1825–1897), Hungarian-born rabbi in Moravia, Croatia, and America
• Jerome Grossman (1917–2013), American activist
• Jiří Grossmann, Czech theatre actor, poet and composer
• Joel Grossman, Professor of Political Science at Johns Hopkins University
• Jonathan Grossman, Revolutionized Corporal Law Theories
• Judith Grossman, American writer
• Karl Grossman, professor of journalism at State University of New York/College at Old Westbury
• Karol Grossmann (1864 – 1929), the first Slovene filmmaker
• Karolien Grosemans, Belgian politician
• Kurt Grossmann, German journalist
• Larry Grossman (composer), composer of Broadway musicals
• Larry Grossman (politician), politician in Ontario, Canada
• Leslie Grossman, American actress
• Lev Grossman, American writer
• Louis Grossmann (1863–1926), Austrian-American rabbi
• Loyd Grossman, Anglo-American television presenter and chef
• Marc Grossman (born 1951), former American ambassador to Turkey
• Marcel Grossmann, Hungarian mathematician
• Mary Belle Grossman (1879 – 1977), American judge and suffragist
• Martin Grossman (1965–2010), American murderer
• Mindy Grossman, CEO of HSN, Inc.
• Nancy Grossman, American artist
• Naomi Grossman, American actress
• Natalia Grossman, (born 2001), American sport climber
• Nicklas Grossmann, Swedish ice hockey player
• Randy Grossman (born 1952), American NFL football player
• Rex Grossman, former NFL quarterback
• Rex Grossman Sr., American football linebacker and fullback
• Richard Grossman (author) (1943–2011), American anti-globalization writer
• Richard Grossman (bassist), bassist for the Hoodoo Gurus and the Divinyls
• Richard Grossman (pianist) (1937–1992), American jazz pianist
• Richard Grossman (publisher), American publisher, founder of Grossman Publishers
• Robbie Grossman, American MLB outfielder
• Robert Grossman, American painter, sculptor, filmmaker, and author
• Robert Lee Grossman, American computer scientist and bioinformatician
• Rudolph Grossman (1867–1927), Austrian-American rabbi
• Sally Grossman, widow of Albert Grossman and operator of the Woodstock-based Bearsville Records
• Sanford J. Grossman, American economist, John Bates Clark Medal winner in 1987
• Siegfried Grossmann, (born 1930), German theoretical physicist
• Stefan Grossman, American guitarist and singer
• Steven Grossman, American politician and investor
• Thomas Grossmann, (born 1951), German writer and psychologist
• Tuvia Grossman, Jewish American student attacked by a violent Arab mob and later wrongly identified as a Palestinian
• Vasily Grossman (Васи́лий Семёнович Гро́ссман, 1905 –1964), Soviet writer and war correspondant
• Victor Grossman (born Stephen Wechsler, 1928), American socialist and writer
• Yitzchak Dovid Grossman, Israeli rabbi - the "Disco Rabbi"

• Grossmann Jet Service, Aviation company in Prague, Czech Republic
• Grossmann, a German place name in Moselle, France