GPS is the Global Positioning System, a satellite-based navigation system.

GPS may also refer to:

• GPS navigation device, especially an automotive navigation system
• Generalized processor sharing, an algorithm to fairly share computer processing time
• General Problem Solver, a 1959 computer program
• Satellite navigation, GPS (global positioning system) in common parlance

• Crossroads GPS (Grassroots Policy Strategies), a nonprofit corporation that works in conjunction with the Super PAC American Crossroads
• Fusion GPS, American commercial and strategic research firm
• Gap Inc. stock ticker
• Ghana Prisons Service
• GPS (band), a progressive rock band
• GPS Rugby, an Australian rugby union club
• Geirus Policies and Standards committee, a body of the Rabbinical Council of America
• Gabungan Parti Sarawak, a Malaysian political coalition based in Sarawak

• Greenwich Public Schools, a school district in Greenwich, Connecticut, US
• Gilbert Public Schools, a school district in Gilbert, Arizona, US
• Girls Preparatory School, an all-girls prep school in Chattanooga, Tennessee, US
• Great Public Schools. In Australia, several associations of boys' private schools

• Athletic Association of the Great Public Schools of New South Wales
• Great Public Schools Association of Queensland Inc.

• Grosse Pointe South High School, a public high school in Grosse Pointe, Michigan, US
• Greenville Public Schools (a.k.a. Greenville Public School District), a school district in Greenville, Mississippi, US
• The School of Global Policy and Strategy, an institute of international studies at the University of California, San Diego

• Goodpasture syndrome, a rare autoimmune disease
• Gray platelet syndrome, a rare congenital autosomal recessive bleeding disorder

• Seymour Airport (IATA code), Galápagos Islands, Ecuador
• Fareed Zakaria GPS (Global Public Square), a CNN television show
• Geometrical Products Specification, an international standard for geometric dimensioning and tolerancing
• Genealogical Proof Standard (see also Cluster genealogy)
• "GPS" (song), a song by Maluma
• "Var är jag", renamed to "GPS", a song by Basshunter from his LOL <(^^,)> album

• Grams of protein per dollar (gP/$), a means of representing the cost of amino acids in a food product