Clarence River may refer to:

• Clarence River (New South Wales), in northern New South Wales, Australia
• Clarence River (Tasmania), in southern Tasmania, Australia
• Clarence River (Alaska–Yukon), rises in the Yukon Territory of Canada and crosses the border several times into the U.S. state of Alaska
• Waiau Toa / Clarence River, on the South Island of New Zealand
• Clarence (river), a tributary of the Lys in northern France