Aloisio or Aloísio is a Romance masculine given name, arising via an Old Occitan form Aloys from Louis.
- Aloisio da Milano, also known as Aloisio da Carezano, Aleviz Milanets and Aleviz Fryazin, 15th/16th century Italian architect
- Aloisio the New, 16th century Italian Renaissance architect
- Aloísio Pires Alves (born 1963), Brazilian footballer (defender)
- Aloísio da Silva Filho (born 1974), Brazilian footballer (goalkeeper)
- Aloísio José da Silva (born 1975), Brazilian footballer (striker)
- Aloísio dos Santos Gonçalves (born 1988), Brazilian footballer (striker)