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An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs).[1][2][3] This in turn leads to increased extracellular concentrations of adenosine and therefore an increase in adenosinergic neurotransmission.
List of AdoRIs
[edit]- Acadesine[4]
- Acetate[4]
- Barbiturates[5][6]
- Benzodiazepines[5][7][8][9][10][11][12]
- Calcium channel blockers[4]
- Carbamazepine[4]
- Carisoprodol[13][14][15]
- Cilostazol[16]
- Cyclobenzaprine[17][18]
- Dilazep[1]
- Dipyridamole[1][19]
- Estradiol[20]
- Ethanol[21]
- Flumazenil[4]
- Hexobendine[22]
- Hydroxyzine[23]
- Indomethacin[4]
- Inosine[24]
- KF24345[25]
- Meprobamate[13][14]
- Nitrobenzylthioguanosine[26]
- Nitrobenzylthioinosine[1][27]
- Papaverine[28]
- Pentoxifylline[29]
- Phenothiazines[17][30]
- Phenytoin[31]
- Progesterone[20]
- Propentofylline[32]
- Propofol[5][33]
- Puromycin[17]
- R75231[34]
- RE 102 BS[35]
- Soluflazine[36][37]
- Toyocamycin[17]
- Tracazolate[23]
- Tricyclic antidepressants[17][18]
See also
[edit]References
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- ^ a b c d e f Goldfrank LR, Neal Flomenbaum, Mary Ann Howland, Robert S. (2006). Goldfrank's toxicologic emergencies. p. 243.
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- ^ Noji T, Nan-ya K, Katagiri C, Mizutani M, Sano J, Nishikawa S, Karasawa A, Kusaka H (2002). "Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice". Pancreas. 25 (4): 387–392. doi:10.1097/00006676-200211000-00011. PMID 12409834. S2CID 24260175.
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