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| Symbol = TXNLA

| AltSymbols = HMW-BCGF, IL14

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}} — '''Interleukin-14''' (IL-14) is a [[cytokine]] that is also called ''High molecular weight [[B-cell]] [[growth factor]]'' (HMW-BCGF) that controls the growth and [[proliferation]] of both normal and cancerous B cells.<ref>Ambrus JL et al., Identification of a cDNA for a human high-molecular-weight B-cell growth factor., 1993, Proceedings of the National Academy of Sciences USA, Volume 90, pages 633—4.</ref> This molecule was also recently designated taxilin.<ref>Nogami,S et al., Taxilin; a novel syntaxin-binding protein that is involved in C — dependent exocytosis in neuroendocrine cells. Genes Cells, 2003, Volume 8, pages 1—28</ref> IL-14 induces B-cell [[proliferation]], inhibits [[antibody]] secretion, and expands selected B-cell subgroups. This [[interleukin]] is produced mainly by [[T cell]]s and certain [[malignant]] B cells. — Two distinct [[transcript]]s are produced from opposite strands of the ''il14'' [[gene]] that are called IL-14α and IL-14β.<ref>Shen, L. et al., Development of Autoimmunity in IL-14-Transgenic Mice. The Journal of Immunology, 2006, Volume 177, pages 567—5686.</ref> The ''il14'' locus is near the gene for [[LCK]] on [[chromosome]] 1 in humans. — ==References==

<references/> — {{immunology-stub}}