THC Science

Allylglycine
Names
	IUPAC name 2-Aminopent-4-enoic acid
Identifiers
CAS Number	7685-44-1;
3D model (JSmol)	Interactive image; Interactive image;
ChemSpider	13425;
ECHA InfoCard	100.028.809
PubChem CID	14044;
CompTox Dashboard (EPA)	DTXSID701313217 ;
	InChI InChI=1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) Key: WNNNWFKQCKFSDK-UHFFFAOYSA-N; InChI=1/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) Key: WNNNWFKQCKFSDK-UHFFFAOYAL;
	SMILES C=CCC(C(=O)O)N; O=C(O)C(N)C\C=C;
Properties
Chemical formula	C5H9NO2
Molar mass	115.13 g/mol
Melting point	265 °C (509 °F; 538 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Allylglycine is a glycine derivative. It is an inhibitor of the enzyme glutamate decarboxylase.^[1] Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter.^[2] It is used to induce convulsions in animals in scientific studies.

References

^ Abshire VM, Hankins KD, Roehr KE, DiMicco JA (1988). "Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local GABA which correlate with increases in heart rate". Neuropharmacology. 27 (11): 1171–7. doi:10.1016/0028-3908(88)90013-5. PMID 3205383. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
^ Sajdyk T, Johnson P, Fitz S, Shekhar A (2008). "Chronic inhibition of GABA synthesis in the bed nucleus of the stria terminalis elicits anxiety-like behavior". J. Psychopharmacol. (Oxford). 22 (6): 633–41. doi:10.1177/0269881107082902. PMID 18308797. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)