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Updating {{chembox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref') per Chem/Drugbox validation (report [[Wikipedia_talk:Wi |
rm invalid alkene-geometry spec in SMILES |
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| InChI = 1/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) |
| InChI = 1/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) |
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| InChIKey = WNNNWFKQCKFSDK-UHFFFAOYAL |
| InChIKey = WNNNWFKQCKFSDK-UHFFFAOYAL |
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| SMILES1 = O=C(O)C(N) |
| SMILES1 = O=C(O)C(N)CC=C |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) |
| StdInChI = 1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8) |
Revision as of 16:12, 16 December 2010
Names | |
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IUPAC name
2-Aminopent-4-enoic acid
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.028.809 |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C5H9NO2 | |
Molar mass | 115.13 g/mol |
Melting point | 265 °C (509 °F; 538 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Allylglycine is a glycine derivative. It is an inhibitor of the enzyme glutamate decarboxylase.[1] Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter.[2] It is used to induce convulsions in animals in scientific studies.
References
- ^ Abshire VM, Hankins KD, Roehr KE, DiMicco JA (1988). "Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local GABA which correlate with increases in heart rate". Neuropharmacology. 27 (11): 1171–7. doi:10.1016/0028-3908(88)90013-5. PMID 3205383.
{{cite journal}}
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ignored (help)CS1 maint: multiple names: authors list (link) - ^ Sajdyk T, Johnson P, Fitz S, Shekhar A (2008). "Chronic inhibition of GABA synthesis in the bed nucleus of the stria terminalis elicits anxiety-like behavior". J. Psychopharmacol. (Oxford). 22 (6): 633–41. doi:10.1177/0269881107082902. PMID 18308797.
{{cite journal}}
: Unknown parameter|month=
ignored (help)CS1 maint: multiple names: authors list (link)