Tilney and Tylney are surnames of English origin. They may refer to:

• Agnes Tilney (AKA Agnes Howard, Duchess of Norfolk, 1477–1545), English noblewoman
• Colin Tilney (born 1933), harpsichordist, fortepianist and teacher
• Edmund Tylney (AKA Edmund Tilney, 1536–1610), courtier to Elizabeth I of England, and Master of the Revels
• Elizabeth Tilney, Countess of Surrey (before 1445 – 1497), English heiress and lady-in-waiting to two queens
• Sir Frederick Tilney (died 1445) Lord of Ashwellthorpe, Norfolk, and Boston, Lincolnshire
• John Tilney (1907–94), British businessman and politician
• Robert Tilney (before 1943 – after 1962), British Army officer who served during World War II
• William S. Tilney (born 1939), American public official, lawyer and diplomat

• Thorpe Tilney, hamlet in the county of Lincolnshire, England
• Tilney All Saints, civil parish in the English county of Norfolk
• Tilney St Lawrence, village and civil parish in the English county of Norfolk

• Tilney (company)

• Henry Tilney (Northanger Abbey)

• Athelney
• Thilmany
• Tillenay
• Tylney