The Business may refer to:
- The Business (magazine), a British weekly magazine
- The Business (novel), a novel by Iain Banks
- The Business (band), an English punk rock/Oi! band
- The Business (film), a 2005 film directed by Nick Love
- The Business, an RTÉ Radio 1 show presented by John Murray
- The Business, a National Public Radio film industry news digest produced by KCRW
- The Business (TV program), an Australian business program
- The Business (TV series)
- "The Business" (Yung Berg song), 2008
- "The Business" (Tiësto song), 2020
- "The Business" a song by X Ambassadors from The Reason
- The Business – the Definitive Singles Collection, a compilation album by Madness