SLX1B
Identifiers
Aliases	SLX1B, GIYD2, Slx1 structure-specific endonuclease subunit homolog b, SLX1 homolog B, structure-specific endonuclease subunit
External IDs	OMIM: 615823 MGI: 1915220 HomoloGene: 11434 GeneCards: SLX1B
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 29,454,501 bp[1] End 29,458,219 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 126,288,640 bp[2] End 126,294,956 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Top expressed in More reference expression data BioGPS n/a
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79008 75764 Ensembl ENSG00000181625 ENSMUSG00000059772 UniProt Q9BQ83 Q8BX32 RefSeq (mRNA) NM_178044 NM_024044 NM_001400286 NM_001400287 NM_029420 RefSeq (protein) NP_001014999 NP_001015000 NP_083696 Location (UCSC) Chr 16: 29.45 – 29.46 Mb Chr 7: 126.29 – 126.29 Mb PubMed search [3] [4]
Wikidata
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SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) is a protein in humans that is encoded by the SLX1B gene. ^[5]

This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010].

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