| S-formylglutathione hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.12 | ||||||||
| CAS no. | 50812-21-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme S-formylglutathione hydrolase (EC 3.1.2.12) catalyzes the reaction
- S-formylglutathione + H2O glutathione + formate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is S-formylglutathione hydrolase. It participates in Methane Metabolism.
References[edit]
- Uotila L (1973). "Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases". Biochemistry. 12 (20): 3938–43. doi:10.1021/bi00744a024. PMID 4200890.
- Uotila L, Koivusalo M (1974). "Purification and properties of S-formylglutathione hydrolase from human liver". J. Biol. Chem. 249 (23): 7664–72. PMID 4436331.
- Harms N, Ras J, Reijnders WN, van Spanning RJ, Stouthamer AH (1996). "S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?". J. Bacteriol. 178 (21): 6296–9. PMC 178503. PMID 8892832.
