| Clinical data | |
|---|---|
| Trade names | Loargys |
| Other names | AEB-1102 |
| Routes of administration | Intravenous |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| PubChem SID | |
| DrugBank | |
| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C1554H2492N416O463S6 |
| Molar mass | 34603.84 g·mol−1 |
Pegzilarginase, sold under the brand name Loargys, is a medication used for the treatment of hyperargininemia.[1][2]
The most common side effects include allergic reactions.[1]
Pegzilarginase was approved for medical use in the European Union in December 2023.[2]
Medical uses[edit]
Pegzilarginase is indicated for the treatment of arginase 1 deficiency, also known as hyperargininemia.[1][2]
Society and culture[edit]
Legal status[edit]
In October 2023, the Committee for Medicinal Products for Human Use adopted a positive opinion, recommending the granting of a marketing authorization under exceptional circumstances for the medicinal product Loargys, intended for the treatment of hyperargininemia.[1] The applicant for this medicinal product is Immedica Pharma AB.[1] Pegzilarginase was approved for medical use in the European Union in December 2023.[2]
Brand names[edit]
Pegzilarginase is the international nonproprietary name.[3]
Pegzilarginase is sold under the brand name Loargys.[1]
References[edit]
- ^ a b c d e f g "Loargys EPAR". European Medicines Agency. 14 July 2016. Retrieved 26 December 2023. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
- ^ a b c d e "Loargys Product information". Union Register of medicinal products. 18 December 2023. Retrieved 26 December 2023.
- ^ World Health Organization (2018). "International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 79". WHO Drug Information. 32 (1). hdl:10665/330941.
External links[edit]
- "Pegzilarginase (Code C125143)". NCI Thesaurus. 27 November 2023. Retrieved 26 December 2023.
