Protein-coding gene in the species Homo sapiens
PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene .[ 5] [ 6] [ 7] [ 8]
PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast , flies , and mammals .[supplied by OMIM][ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000115687 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026274 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, Wenger RH (Nov 2001). "Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors" (PDF) . Biochem Biophys Res Commun . 288 (4): 757–64. doi :10.1006/bbrc.2001.5840 . PMID 11688972 . Archived from the original (PDF) on 2013-11-02. Retrieved 2018-12-22 .
^ Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL (Aug 2001). "PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase" . Proc Natl Acad Sci U S A . 98 (16): 8991–6. Bibcode :2001PNAS...98.8991R . doi :10.1073/pnas.161284798 . PMC 55361 . PMID 11459942 .
^ da Silva Xavier G, Rutter J, Rutter GA (Jun 2004). "Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose" . Proc Natl Acad Sci U S A . 101 (22): 8319–24. Bibcode :2004PNAS..101.8319D . doi :10.1073/pnas.0307737101 . PMC 420392 . PMID 15148392 .
^ a b "Entrez Gene: PASK PAS domain containing serine/threonine kinase" .
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Activity Regulation Classification Kinetics Types