| nucleotide diphosphokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.6.4 | ||||||||
| CAS no. | 53167-92-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a nucleotide diphosphokinase (EC 2.7.6.4) is an enzyme that catalyzes the chemical reaction
- ATP + nucleoside 5'-phosphate AMP + 5'-phosphonucleoside 3'-diphosphate
Thus, the two substrates of this enzyme are ATP and nucleoside 5'-phosphate, whereas its two products are AMP and 5'-phosphonucleoside 3'-diphosphate.
This enzyme belongs to the family of transferases, specifically those transferring two phosphorus-containing groups (diphosphotransferases). The systematic name of this enzyme class is ATP:nucleoside-5'-phosphate diphosphotransferase. Other names in common use include nucleotide pyrophosphokinase, ATP:nucleotide pyrophosphotransferase, ATP nucleotide 3'-pyrophosphokinase, and nucleotide 3'-pyrophosphokinase.
References[edit]
- Murao S, Nishino T (1974). "Isolation and identification of ATP:nucleotide pyrophosphotransferase-producing microorganism". Agric. Biol. Chem. 38 (12): 2483–2489. doi:10.1271/bbb1961.38.2483.
- Nishino T, Murao S (1974). "Purification and some properties of ATP:nucleotide pyrophosphotransferase of Streptomyces adephospholyticus". Agric. Biol. Chem. 38 (12): 2491–2496. doi:10.1271/bbb1961.38.2491.
- Nishino T, Murao S (1975). "Characterization of pyrophosphoryl transfer reaction of ATP:nucleotide pyrophosphotransferase". Agric. Biol. Chem. 39 (5): 1007–1014. doi:10.1271/bbb1961.39.1007.
