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Names | |
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IUPAC name
N-Oxaloglycine
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Systematic IUPAC name
[(Carboxymethyl)amino](oxo)acetic acid | |
Identifiers | |
3D model (JSmol)
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Abbreviations | NOG |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.213.188 |
MeSH | oxalylglycine |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C4H5NO5 | |
Molar mass | 147.086 g·mol−1 |
Appearance | Colorless solid |
log P | 1.232 |
Acidity (pKa) | 2.827 |
Basicity (pKb) | 11.170 |
Related compounds | |
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N-Oxalylglycine is the organic compound with the formula HO2CC(O)NHCH2CO2H. This colourless solid is used as an inhibitor of α-ketoglutarate-dependent enzymes.[1] It is isosteric with α-Ketoglutaric acid. Such enzymes are pervasive and, for example, are required for the synthesis of 4-hydroxyproline.
References
[edit]- ^ Hausinger, R. P."Fe(II)/α-ketoglutarate-dependent hydroxylases and related enzymes" Critical Reviews of Biochemical Molecular Biology 2004, 39: pp 21-68. doi:10.1080/10409230490440541