| lysine-pyruvate 6-transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.71 | ||||||||
| CAS no. | 114189-79-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction
- L-lysine + pyruvate ⇌ L-2-aminoadipate 6-semialdehyde + L-alanine
Thus, the two substrates of this enzyme are L-lysine and pyruvate, whereas its two products are L-2-aminoadipate 6-semialdehyde and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-lysine:pyruvate aminotransferase. Other names in common use include lysine-pyruvate aminotransferase, and Lys-AT.
References[edit]
- Schmidt H, Bode R, Birnbaum D (1988). "A novel enzyme, L-lysine : pyruvate aminotransferase, catalyses the first step of lysine catabolism in Pichia guilliermondii". FEMS Microbiol. Lett. 49 (2): 203–206. doi:10.1111/j.1574-6968.1988.tb02716.x.
