THC Science

KDM8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UYJ, 4AAP, 4GAZ, 4GJY, 4GJZ, 4QU1
Identifiers
Aliases	KDM8, JMJD5, lysine demethylase 8
External IDs	OMIM: 611917 MGI: 1924285 HomoloGene: 49791 GeneCards: KDM8
Gene location (Human)
Chr.	Chromosome 16 (human)
End	27,221,768 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	125,061,441 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	79831
	77035
	ENSG00000155666
	ENSMUSG00000030752
	Q8N371
	Q9CXT6
	NM_001145348; NM_024773
	NM_029842
	NP_001138820; NP_079049
	NP_084118
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene.^[5]

Function[edit]

This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000155666 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030752 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Lysine demethylase 8". Retrieved 2016-04-09.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.