Jean-Bernard is a French masculine given name. It may refer to :

• Jean-Bernard Gauthier de Murnan (1748–1796), a French officer for the Continental Army
• Jean-Bernard Knepper (1638–1698), a Luxembourg advocat and notary
• Jean-Bernard Ndongo Essomba, a Cameroonian politician
• Jean-Bernard Racine (born 1940), a Swiss Professor of geography
• Jean-Bernard Raimond (1926–2016), a conservative French politician
• Jean-Bernard Restout (1732–1797), a French painter
• Jean Bernard Sindeu, a Cameroonian politician

• Jean Bernard (disambiguation)
• Jean-Bernard, abbé Le Blanc (1707–1781), a French art critic
• Marc Jean-Bernard (born 1952), a French/American philosopher, classical musician and musicologist
• Gouffre Jean-Bernard, one of the deepest known caves in the world