Dead Hand was a Soviet weapons-control system during the Cold War.
Dead Hand or Dead hand may also refer to:
- The Dead Hand, 2009 book by David E. Hoffman
- Dead Hand, or Mortmain, the perpetual, inalienable ownership of real estate
- The "Dead Hand" series, books by Upton Sinclair starting with The Profits of Religion
- "Dead Hand", later retitled "The General", a 1945 novella by Isaac Asimov later collected in Foundation and Empire (1952)
- "Dead Hand" (The Americans), a 2018 episode of the TV series The Americans
- Dead hand (cards), a hand that is dealt but not used during a card game
- So-called "Dead hand control," also known as the rule against perpetuities, in common law property law