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Names | |
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IUPAC name
1-chloro-3-fluoro-2-methylbenzene
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.006.494 |
EC Number |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C7H6ClF | |
Molar mass | 144.57 g·mol−1 |
Boiling point | 154–156 °C (309–313 °F) |
Hazards | |
GHS labelling: | |
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Warning | |
H226, H302, H312, H315, H332, H335 | |
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P321, P330, P362+P364, P370+P378, P403+P233, P403+P235, P405, P501 | |
Flash point | 46 °C (115 °F) |
Related compounds | |
Related compounds
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2-Chloro-6-fluorobenzaldehyde, toluene |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2-Chloro-6-fluorotoluene (CFT) is a halogenated derivative of toluene that is used as an intermediate in numerous organic syntheses.[1][2]
Uses
[edit]CFT is used to prepare 2-chloro-6-fluorobenzaldehyde via oxidation with hydrogen peroxide, which forms an aldehyde group.[2]
![](https://upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Preperation_of_2-chloro-6-fluorobenzaldehyde.png/220px-Preperation_of_2-chloro-6-fluorobenzaldehyde.png)
CFT is also used in the preparation of 4-chloro-1H-indazole.[1]
References
[edit]- ^ a b Meng, Ge; Yang, Tao; Liu, Yang (2011). "An Improved Preparation of 4-Chloro-1 H -indazole". Organic Preparations and Procedures International. 43 (4): 354–359. doi:10.1080/00304948.2011.594005. ISSN 0030-4948. S2CID 96965570.
- ^ a b Bunnett, J. F.; Miles, J. H.; Nahabedian, K. V. (1961). "Kinetics and Mechanism of the Alkali Cleavage of 2,6-Dihalobenzaldehydes 1". Journal of the American Chemical Society. 83 (11): 2512–2516. doi:10.1021/ja01472a022. ISSN 0002-7863.