Purgation may refer to:

• Inducing bowel movement with a laxative
• The purification of the soul
  • In this life, see State (theology)
  • In Purgatory
• Purgation (album), Trigger the Bloodshed album
• In US patent law, purgation of misuse refers to discontinuance of a restrictive practice and dissipation of its adverse results – see B.B. Chemical Co. v. Ellis