One Way Street may refer to:

• one-way traffic
• One Way Street (1925 film), a 1925 American drama film directed by John Francis Dillon
• One Way Street, a 1950 American crime film directed by Hugo Fregonese
• One Way Street (book), a 1928 anthology of brief meditations by Walter Benjamin
• "One Way Street", song by Michael Learns to Rock from the album Blue Night
• "One Way Street", song by Soup Dragons from the album Hydrophonic
• "One Way Street", song by Aerosmith from the album Aerosmith
• "One Way Street", song by Go West from the album Bangs & Crashes