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Names | |
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IUPAC name
17β-Hydroxy-5α-androstane-3,11-dione
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Systematic IUPAC name
(1S,3aS,3bS,5aS,9aS,9bS,11aS)-1-Hydroxy-9a,11a-dimethyltetradecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione | |
Other names
11-Oxodihydrotestosterone; 5α-Androstan-17β-ol-3,11-dione; 11-KDHT
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C19H28O3 | |
Molar mass | 304.43 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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11-Ketodihydrotestosterone (11-KDHT), also known as 5α-androstan-17β-ol-3,11-dione, is an endogenous, naturally occurring steroid and androgen prohormone that is produced primarily, if not exclusively, in the adrenal glands.[1] It is closely related to 11β-hydroxyandrostenedione (11β-KA4), adrenosterone (11-ketoandrostenedione; 11-KA4), and 11-ketotestosterone (11-KT), which are also produced in the adrenal glands.[1]
See also
[edit]References
[edit]- ^ a b Pretorius E, Arlt W, Storbeck KH (February 2017). "A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids" (PDF). Molecular and Cellular Endocrinology. 441: 76–85. doi:10.1016/j.mce.2016.08.014. PMID 27519632. S2CID 4079662.