This article briefly reviews current knowledge about AIDS-related stigma, defined as prejudice, discounting, discrediting, and discrimination directed at people perceived to have AIDS or HIV, and the individuals, groups, and communities with which they are associated. AIDS stigma has been manifested in discrimination, violence, and personal rejection of people with AIDS (PWAs). Whereas the characteristics of AIDS as an illness probably make some degree of stigma inevitable, AIDS has also been used as a symbol for expressing negative attitudes toward groups disproportionately affected by the epidemic, especially gay men and injecting drug users (IDUs). AIDS stigma affects the well-being of PWAs and influences their personal choices about disclosing their serostatus to others. It also affects PWAs' loved ones and their caregivers, both volunteers and professionals. Stigma has hindered society's response to …