Adrenal C11-oxy C21 steroids contribute to the C11-oxy C19 steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone L Barnard, R Gent, D Van Rooyen, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 174, 86-95, 2017 | 35 | 2017 |
The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway D van Rooyen, R Gent, L Barnard, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 178, 203-212, 2018 | 32 | 2018 |
CYP17A1 exhibits 17αhydroxylase/17, 20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway D Van Rooyen, R Yadav, EE Scott, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 199, 105614, 2020 | 19 | 2020 |
Analysis of 52 C19 and C21 steroids by UPC2-MS/MS: Characterising the C11-oxy steroid metabolome in serum T du Toit, D van Rooyen, MA Stander, SL Atkin, AC Swart Journal of Chromatography B 1152, 122243, 2020 | 11 | 2020 |
The metabolic fate and receptor interaction of 16α-hydroxyprogesterone and its 5α-reduced metabolite, 16α-hydroxy-dihydroprogesterone D van Rooyen, T du Toit, R Louw-du Toit, D Africander, P Swart, AC Swart Molecular and cellular endocrinology 441, 86-98, 2017 | 7 | 2017 |
C11-hydroxy and C11-oxo C19 and C21 Steroids: Pre-Receptor Regulation and Interaction with Androgen and Progesterone Steroid Receptors R Gent, D Van Rooyen, SL Atkin, AC Swart International Journal of Molecular Sciences 25 (1), 101, 2023 | 1 | 2023 |
Investigating the biosynthesis and metabolism of 11β-hydroxyandrostenedione AC Swart, D van Rooyen, T du Toit Methods in Enzymology 689, 387-431, 2023 | 1 | 2023 |
Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism D van Rooyen, AM Lerario, DW Little III, MR Ullenbruch, MJ Taylor, ... Molecular and Cellular Endocrinology, 112176, 2024 | | 2024 |
FRI192 Serum Steroid Biomarkers For The Differential Diagnosis Of Adrenocortical Carcinoma (ACC) And Adrenocortical Adenoma (ACA) D van Rooyen, R Scheske, AM Lerario, WE Rainey, RJ Auchus, ... Journal of the Endocrine Society 7 (Supplement_1), bvad114. 187, 2023 | | 2023 |
SAT263 Osteocalcin Promotes Cortisol Production In Human Adrenal Cells R Scheske, D van Rooyen, WE Rainey Journal of the Endocrine Society 7 (Supplement_1), bvad114. 268, 2023 | | 2023 |
LBMON273 Not All Men Are Created Equal D van Rooyen, SL Atkin, AC Swart Journal of the Endocrine Society 6 (Suppl 1), A651, 2022 | | 2022 |
OR13-5 Bone Morphogenetic Protein-4 (BMP4) Inhibits Adrenal Cell Cortisol Synthesis by Blocking CYP17A1 and CYP11B1 Expression. S Garber, WE Rainey, J Rege, D van Rooyen, AG Lopez Journal of the Endocrine Society 6 (Supplement_1), A86-A86, 2022 | | 2022 |
Primary aldosteronism caused by a pI157S somatic KCNJ5 mutation in a black adolescent female with aldosterone-producing adenoma CE Gomez-Sanchez, D van Rooyen, WE Rainey, K Nanba, AR Blinder, ... Frontiers in Endocrinology 13, 921449, 2022 | | 2022 |
CYP11B and CYP17A1 in the Biosynthesis and Metabolism of C11‐oxy Steroids AC Swart, D van Rooyen, R Gent, T du Toit The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
An investigation into the biosynthesis and metabolism of adrenal C11-oxy steroids D Van Rooyen | | 2020 |
OR02-5 Novel Intermediates Are Catalysed By 11βHSD And CYP17A1 In The C11-oxy Backdoor Pathway Leading To The Production Of 11-ketodihydrotestosterone A Swart, S Atkin, D Van Rooyen Journal of the Endocrine Society 3 (Supplement_1), OR02-5, 2019 | | 2019 |
The metabolism of adrenal 11beta-hydroxyprogesterone, 11keto-progesterone and 16alpha-hydroxyprogesterone by steroidogenic enzymes D Van Rooyen Stellenbosch: Stellenbosch University, 2017 | | 2017 |
The metabolic fate and receptor interaction of 16a-hydroxyprogesterone and its 5a-reduced metabolite, 16a-hydroxy-dihydroprogesterone D van Rooyen, T du Toit, R Louw-du Toit, D Africander, P Swart, AC Swart Molecular and Cellular Endocrinology 30, 1e13, 2016 | | 2016 |
Adrenal C11-oxy C21 steroids contribute to the C11-oxy L Barnard, R Gent, D van Rooyen Endocr. Rev 21, 245-291, 2000 | | 2000 |