Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by maintenance of cAMP homeostasis H Khan, P Paul, H Goar, B Bamniya, N Baid, D Sarkar eLife 13, 2024 | | 2024 |
Dual functioning by the PhoR sensor is a key determinant to Mycobacterium tuberculosis virulence PR Singh Plos Genetics 19 (12), e1011700, 2023 | 4 | 2023 |
Molecular connectivity between extracytoplasmic sigma factors and PhoP accounts for coupled mycobacterial stress response H Goar, P Paul, H Khan, D Sarkar Journal of bacteriology 204 (6), e00110-22, 2022 | 7 | 2022 |
Metabolic Switching of Mycobacterium tuberculosis during Hypoxia Is Controlled by the Virulence Regulator PhoP PR Singh, AK Vijjamarri, D Sarkar Journal of bacteriology 202 (7), 10.1128/jb. 00705-19, 2020 | 26 | 2020 |
Functioning of mycobacterial heat shock repressors requires the master virulence regulator PhoP RR Sevalkar, D Arora, PR Singh, R Singh, VK Nandicoori, S Karthikeyan, ... Journal of bacteriology 201 (12), 10.1128/jb. 00013-19, 2019 | 16 | 2019 |
Characteristics of the essential pathogenicity factor Rv1828, a MerR family transcription regulator from Mycobacterium tuberculosis S Singh, RR Sevalkar, D Sarkar, S Karthikeyan The FEBS journal 285 (23), 4424-4444, 2018 | 10 | 2018 |
Mycobacterium tuberculosis virulence‐regulator PhoP interacts with alternative sigma factor SigE during acid‐stress response R Bansal, V Anil Kumar, RR Sevalkar, PR Singh, D Sarkar Molecular microbiology 104 (3), 400-411, 2017 | 55 | 2017 |
EspR Protein-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP* ( doi: 10.1074/jbc.M116.746289) V Anil Kumar, R Goyal, R Bansal, N Singh, RR Sevalkar, A Kumar, ... Journal of Biological Chemistry, 2016 | 49* | 2016 |
Solution structure of the PhoP DNA -binding domain from Mycobacterium tuberculosis R Macdonald, D Sarkar, BR Amer, RT Clubb Journal of Biomolecular NMR 63 (1), 111-117, 2015 | 2 | 2015 |
Probing protease sensitivity of recombinant human erythropoietin reveals α3-α4 inter-helical loop as a stability determinant. JS Samuel, K Deepak, SB Chodisetti, JN Agrewala, B Singh, ... Proteins: Structure, Function and Bioinformatics 83 (10), 1813-1822., 2015 | | 2015 |
A transcriptional co‐repressor regulatory circuit controlling the heat‐shock response of Mycobacterium tuberculosis R Singh, V Anil Kumar, AK Das, R Bansal, D Sarkar Molecular microbiology 94 (2), 450-465, 2014 | 20 | 2014 |
Unique N-terminal arm of Mycobacterium tuberculosis PhoP protein plays an unusual role in its regulatory function AK Das, VA Kumar, RR Sevalkar, R Bansal, D Sarkar Journal of Biological Chemistry 288 (40), 29182-29192, 2013 | 8 | 2013 |
Phosphorylation of PhoP protein plays direct regulatory role in lipid biosynthesis of Mycobacterium tuberculosis R Goyal, AK Das, R Singh, PK Singh, S Korpole, D Sarkar Journal of Biological Chemistry 286 (52), 45197-45208, 2011 | 57 | 2011 |
A single-amino-acid substitution in the C terminus of PhoP determines DNA-binding specificity of the virulence-associated response regulator from Mycobacterium tuberculosis AK Das, A Pathak, A Sinha, M Datt, B Singh, S Karthikeyan, D Sarkar Journal of molecular biology 398 (5), 647-656, 2010 | 17 | 2010 |
Domain structure of virulence-associated response regulator PhoP of Mycobacterium tuberculosis: role of the linker region in regulator-promoter interaction(s) A Pathak, R Goyal, A Sinha, D Sarkar Journal of Biological Chemistry 285 (45), 34309-34318, 2010 | 31 | 2010 |
Mycobacterium tuberculosis PhoP Recognizes Two Adjacent Direct-Repeat Sequences To Form Head-to-Head Dimers S Gupta, A Pathak, A Sinha, D Sarkar Journal of bacteriology 191 (24), 7466-7476, 2009 | 38 | 2009 |
PhoP-PhoP interaction at adjacent PhoP binding sites is influenced by protein phosphorylation A Sinha, S Gupta, S Bhutani, A Pathak, D Sarkar Journal of bacteriology 190 (4), 1317-1328, 2008 | 57 | 2008 |
Transcriptional autoregulation by Mycobacterium tuberculosis PhoP involves recognition of novel direct repeat sequences in the regulatory region of the promoter S Gupta, A Sinha, D Sarkar FEBS letters 580 (22), 5328-5338, 2006 | 84 | 2006 |
Nucleotide-induced conformational change in the catalytic subunit of the phosphate-specific transporter from M. tuberculosis: Implications for the ATPase structure S Gupta, PK Chakraborti, D Sarkar Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1750 (2), 112-121, 2005 | 4 | 2005 |
Identification of the λ integrase surface that interacts with Xis reveals a residue that is also critical for Int dimer formation D Warren, MD Sam, K Manley, D Sarkar, SY Lee, M Abbani, JM Wojciak, ... Proceedings of the National Academy of Sciences 100 (14), 8176-8181, 2003 | 39 | 2003 |