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richard gaynor
richard gaynor
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Verified email at biontech.us
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Cited by
Year
A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease
A Zuiani, CL Dulberger, NS De Silva, M Marquette, YJ Lu, GM Palowitch, ...
Cell, 2024
42024
769 Interim clinical and translational data from NTC-001, a phase I study to evaluate the non-engineered neoantigen-specific T cell product BNT221 in patients with advanced or …
JSW Borgers, D Lenkala, B McCarthy, V Kohler, S Hymson, E Jackson, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
1017O NTC-001: A phase I study to test safety and efficacy of BNT221, a non-engineered neoantigen-specific T cell product, in patients with advanced or metastatic melanoma
JSW Borgers, D Lenkala, B McCarthy, V Kohler, S Hymson, K Esaulova, ...
Annals of Oncology 34, S619, 2023
22023
The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection
CM Arieta, YJ Xie, DA Rothenberg, H Diao, D Harjanto, S Meda, ...
Cell 186 (11), 2392-2409. e21, 2023
312023
Coronavirus vaccines and methods of use
RB Gaynor, L Srinivasan, A Poran, D Harjanto, C Kuksin, DA Rothenberg, ...
US Patent App. 17/912,841, 2023
22023
Coronavirus vaccines and methods of use
RB Gaynor, L Srinivasan, A Poran, D Harjanto, C Kuksin, DA Rothenberg, ...
US Patent App. 17/481,781, 2023
12023
Coronavirus vaccines and methods of use
RB Gaynor, L SRINIVASAN, A PORAN, D HARJANTO, C KUKSIN, ...
2023
A universal MHCII technology platform to characterize antigen-specific CD4+ T cells
R Vyasamneni, V Kohler, B Karki, G Mahimkar, E Esaulova, J McGee, ...
Cell Reports Methods 3 (1), 2023
22023
Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer
MM Awad, R Govindan, KN Balogh, DR Spigel, EB Garon, ME Bushway, ...
Cancer Cell 40 (9), 1010-1026. e11, 2022
732022
Compositions and methods for preparing t cell compositions and uses thereof
R Ang, V Juneja, R Gaynor
US Patent App. 17/599,468, 2022
2022
Validation of Predicted Neoantigens in Patient Derived Material by Targeted Mass Spectrometry
K Marquart, T Kohler, M Bushway, K Balogh, M Kirsh, MS Rooney, ...
Molecular & Cellular Proteomics 21 (8), S48-S48, 2022
2022
Combination therapy with neoantigen vaccine
R Ang, R Gaynor, M Goldstein
US Patent App. 17/251,285, 2021
2021
201 BNT221, an autologous neoantigen-specific T-cell product for adoptive cell therapy of metastatic ovarian cancer
C Arieta, D Velez, S Hannes, S Meda, B McCarthy, D Lenkala, D Harjanto, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
2021
Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations
J Choi, SP Goulding, BP Conn, CD McGann, JL Dietze, J Kohler, ...
Cell reports methods 1 (5), 2021
312021
Coronavirus vaccines and methods of use
RB Gaynor, L SRINIVASAN, A PORAN, D HARJANTO, C KUKSIN, ...
2021
A personal neoantigen vaccine NEO-PV-01 in combination with chemotherapy and pembrolizumab induces broad de novo immune responses in first-line non-squamous NSCLC: Associations …
MM Awad, R Govindan, DR Spigel, EB Garon, V Kohler, R Vyasamneni, ...
Cancer Research 81 (13_Supplement), 73-73, 2021
22021
Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction
JG Abelin, D Harjanto, M Malloy, P Suri, T Colson, SP Goulding, ...
Immunity 54 (2), 388, 2021
82021
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes
A Poran, D Harjanto, M Malloy, CM Arieta, DA Rothenberg, D Lenkala, ...
Genome medicine 12, 1-15, 2020
822020
Combined TCR repertoire profiles and blood cell phenotypes predict melanoma patient response to personalized neoantigen therapy plus anti-PD-1
A Poran, J Scherer, ME Bushway, R Besada, KN Balogh, A Wanamaker, ...
Cell Reports Medicine 1 (8), 2020
382020
Abstract PO-015: Systematic discovery of KRAS neoantigens
J Choi, SP Goulding, BP Conn, CD McGann, JL Dietze, J Kohler, ...
Cancer Research 80 (22_Supplement), PO-015-PO-015, 2020
2020
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