The Tisza or Tisa is a river in Central Europe.
Tisza may also refer to:
- István Tisza (1861–1918), Hungarian prime minister, during World War I
- Kálmán Tisza (1830–1902), Hungarian prime minister
- Kata Tisza (born 1980), Hungarian writer
- Lajos Tisza (1832–1898), Hungarian politician
- Laszlo Tisza (1907–2009), Hungarian physicist and philosopher of science
- Tisza Cipő, a Hungarian sports shoe brand
- Tisza culture an archaeological culture from Hungary
- TISZA Party, a Hungarian political party affiliated with Péter Magyar