Talc is a mineral composed of magnesium silicate.

TALC may refer to:

• The American Lutheran Church, a Christian Protestant denomination in the United States
• Shaw PPV, a Canadian pay-per-view television network whose French language channels use the branding TALC
• Teaching-aids at Low Cost or TALC a British charitable development agency that works to improve access to healthcare in low income countries
• Transport and logistics centre, a national policy and practice research centre based in Sydney, Australia
• Transportation and Land Use Coalition, a non-profit organization in the San Francisco Bay Area, United States