Presumed Guilty may refer to:

Film and television[edit]

• Presumed Guilty (film), a 2008 Mexican documentary film
• Presumed Guilty, a 2002 PBS documentary about the San Francisco Public Defender's office
• "Presumed Guilty", an episode of the TV series CSI: Miami that aired on February 9, 2009

Literature[edit]

• Presumed Guilty: The Tragedy of the Rodney King Affair, a 1992 book by Stacey Koon
• Presumed Guilty: British Legal System Exposed, a 1993 book by Michael Mansfield and Tony Wardle
• Presumed Guilty, a 1993 romantic suspense novel by Tess Gerritsen
• Presumed Guilty: Brian Mulroney, the Airbus Affair, and the Government of Canada, a 1998 book by William Kaplan
• Presumed Guilty: When Cops get it Wrong and Courts Seal the Deal, a 2013 non-fiction book by Bret Christian