McReynolds is a surname that refers to:

• Allen McReynolds (1877-1960), American politician, Missouri senator
• Andrew T. McReynolds (1808-1998), American military officer and lawyer
• Brandon McReynolds (born 1991), American stock car racing driver
• Brian McReynolds (born 1965), American ice hockey player
• Cliff McReynolds, American artist
• David McReynolds (1929-2018), American Socialist
• Faris McReynolds (born 1977), American artist and musician
• James Clark McReynolds (1862–1946), American judge, attorney general, and Supreme Court justice
• Jesse McReynolds (1929–2023), American bluegrass musician
• Jonathan McReynolds (born 1989), American gospel musician
• Kevin McReynolds (born. 1959), American professional baseball player
• Larry McReynolds (born 1959), American race car crew chief
• Madison McReynolds (born 1993), American actress
• Peter McReynolds, Northern Irish politician
• Sam D. McReynolds (1872–1939), American politician from Tennessee
• Thales McReynolds (1943-1988), American baseball player
• Tiffani McReynolds (born 1991), American hurdler