MDH may refer to:

Chemistry[edit]

• Malate dehydrogenase
• (S)-mandelate dehydrogenase
• Methanol dehydrogenase (cytochrome c)
• Methylenedioxyhydroxyamphetamine

Health and medicine[edit]

• Manila Doctors Hospital, in Ermita, Manila, Philippines
• Mater Dei Hospital, in Msida, Malta
• Milton District Hospital, in Milton, Ontario, Canada
• Minnesota Department of Health

Other uses[edit]

• MDH (spice company), an Indian spice producer and seller
• Maguindanao language (ISO 639-3: mdh)
• Mälardalen University College (Mälardalens högskola; MdH), in Sweden
• Minimum descent height, for aircraft landing; see List of aviation, avionics, aerospace and aeronautical abbreviations
• Multidimensional hierarchical toolkit
• Southern Illinois Airport (IATA: MDH)