José Velásquez may refer to:
- José Velásquez (explorer) (1717–1785), Spanish explorer
- José Velásquez (footballer, born 1952), Peruvian footballer
- José Velásquez (footballer, born 1998), Peruvian footballer
- José Antonio Velásquez (1906–1983), Honduran painter
- José David Velásquez (born 1989), Honduran footballer
- José Manuel Velázquez (born 1990), Venezuelan footballer
- José Miguel Velásquez (born 1967), Venezuelan-born composer, music producer and vocal coach