GHS may refer to:

Education[edit]

• Gaithersburg High School, Gaithersburg, Maryland, US
• Glendora High School, a school in Glendora, Los Angeles, US
• Glenunga International High School, formerly Glenunga High School, a school in Adelaide, South Australia
• Gloucester High School (Virginia), a school in Gloucester, Virginia, US
• Grafton High School (disambiguation), several schools
• Grant High School (disambiguation), several schools
• Greenwich High School, Greenwich, Connecticut, US
• Greenwood High School (disambiguation), several schools
• Guam High School (disambiguation), several schools
• Gulf Harbour School, Whangaparaoa, Auckland, New Zealand

Healthcare[edit]

• Geisinger Health System, Pennsylvania, US
• Ghana Health Service
• Global Health Security Index

Other uses[edit]

• GHS (strings), a US guitar string manufacturer
• General Household Survey, UK
• Georgia Historical Society, US
• Ghanaian cedi, currency
• Globally Harmonized System of Classification and Labelling of Chemicals
• Green Hills Software, an American software company
• Growth hormone secretagogue