Christopher Coyne may refer to:
- Christopher J. Coyne (born 1958), coadjutor archbishop of the Roman Catholic Archdiocese of Hartford, Connecticut
- Christopher Coyne (professor) (born 1977), professor of economics
- Chris Coyne (born 1978), Australian (soccer) footballer
- Chris Coyne, Internet entrepreneur who co-founded the websites OkCupid, keybase and SparkNotes